Organic Chemistry – Biomolecules

Ever wanted to know the story of creation from a non biological point of view? Look no further! Biomolecules is the very story that you were looking for. After all, it is DNA that gives us the traits that make us… it is Proteins, Vitamins and Sugars that give us the fuel to feed the fire of life. Let’s have a look at what this unit entails and what all do we need to know at the JEE/NEET level.

Tips And Tricks :

  • The chapter kicks off with an introduction to a basic study of amino acids, their Isoelectric points, and the different types of amino acids. This is an essential part of this chapter and purely logical. It’s important to practice a lot of questions on the isoelectronic points of amino acids.
  • Certain amino acids are essential to know structurally. Say for example, glycine, alanine and valine. A few more are important too. Note them and revise frequently to permanently affix them in your minds.
  • Sugars and their classification is the next important part. Much more important, however, are the structures of glucose/fructose and other D-aldoses. There are 15 in total. Here is a table to help you memorize.
  • Haworth and Fisher projections of glucose and fructose are of prime importance, as are the concepts of Mutarotation and Reducing Sugars. Read them from LG Wade or your coaching material.
  • Protein structures are another important concept and you should be very clear with what each terms means – Primary structure, secondary structure, tertiary structure and quaternary structure.
  • Catalysts and enzymes are important, though not as much as the concepts mentioned above. You should just know what mechanism is followed by enzymes and catalysts and how they affect reactions (Reduce activation energy or change mechanism, but do not alter Enthalpy change of the reaction. This ensures that only kinetics is affected, and not the thermodynamics/equilibrium of the reactions).

That’s all for Biomolecules. Note these concepts well, practice a lot of questions (especially from MS Chouhan : Advanced Problems in JEE) and revise frequently.

All the best,

Aakash Kapoor.

11 thoughts on “Organic Chemistry – Biomolecules”

  1. We want more on organic!!!!
    Thanks for your blog man πŸ™‚
    Logical approach on organic might be more helpful πŸ™‚

    1. I’ll be writing a lot more on organic. In fact, another article is going to be published today only about organic.

    1. Even to remember their relative configuration there is a trick

      configuration wrt OH

      L-Left hand side
      R-Right Hand side

      for all D Aldohexoses(From the second to last carbon)

      Allose- {R,R,R,R}
      Altose- {L,R,R,R}
      Glucose {R,L,R,R}
      Mannose {L,L,R,R}
      Gulose {R,R,L,R}
      Indose {L,R,L,R}
      Galactose- {R,L,L,R}
      Talose {L,L,L,R}

      Logic-the first in the set -{RL,RL,RL,RL]-C2 epimers
      second one-{RR,LL,RR,LL}
      third one-{RRRR,LLLL}
      Last one as all are D is {RRRRRRRR}

      With this if we can remember the aldo pentose from which this is produced we can get its configuration as well

Let me know what you think in the comments below !